3kga
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
{{Seed}} | {{Seed}} | ||
| - | [[Image:3kga. | + | [[Image:3kga.png|left|200px]] |
<!-- | <!-- | ||
| Line 50: | Line 50: | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 09:55:56 2010'' |
Revision as of 07:55, 17 February 2010
Crystal structure of MAPKAP kinase 2 (MK2) complexed with a potent 3-aminopyrazole ATP site inhibitor
Template:ABSTRACT PUBMED 20060294
About this Structure
3KGA is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Velcicky J, Feifel R, Hawtin S, Heng R, Huppertz C, Koch G, Kroemer M, Moebitz H, Revesz L, Scheufler C, Schlapbach A. Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaffold hopping strategy. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1293-7. Epub 2009 Nov 3. PMID:20060294 doi:10.1016/j.bmcl.2009.10.138
Page seeded by OCA on Wed Feb 17 09:55:56 2010
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Be, C. | Huppertz, C. | Izaac, A. | Kroemer, M. | Pflieger, D. | Scheufler, C. | Schlapbach, A. | Velcicky, J. | 3-aminopyrazole scaffold | Activation loop deletion | Alternative splicing | Atp-binding | Atp-site kinase inhibitor | Induced fit | Kinase | Novel hydrophobic pocket | Nucleotide-binding | Phosphoprotein | Polymorphism | Scaffold hoping | Serine/threonine-protein kinase | Small molecule inhibitor | Transferase
