2w0x
From Proteopedia
(Difference between revisions)
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===FACTOR INHIBITING HIF-1 ALPHA WITH PYRIDINE 2,4 DICARBOXYLIC ACID=== | ===FACTOR INHIBITING HIF-1 ALPHA WITH PYRIDINE 2,4 DICARBOXYLIC ACID=== | ||
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| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20822901}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20822901 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_20822901}} | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:12446723</ref><references group="xtra"/> | + | <ref group="xtra">PMID:20822901</ref><ref group="xtra">PMID:12446723</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Peptide-aspartate beta-dioxygenase]] | [[Category: Peptide-aspartate beta-dioxygenase]] | ||
| Line 25: | Line 31: | ||
[[Category: Mcdonough, M A.]] | [[Category: Mcdonough, M A.]] | ||
[[Category: Schofield, C J.]] | [[Category: Schofield, C J.]] | ||
| - | [[Category: 2-oxoglutarate]] | ||
| - | [[Category: Asparaginyl hydroxylase]] | ||
[[Category: Dioxygenase]] | [[Category: Dioxygenase]] | ||
| - | [[Category: Dsbh]] | ||
| - | [[Category: Fih]] | ||
| - | [[Category: Hif]] | ||
[[Category: Hydroxylase]] | [[Category: Hydroxylase]] | ||
[[Category: Hypoxia]] | [[Category: Hypoxia]] | ||
| - | [[Category: Iron]] | ||
| - | [[Category: Metal-binding]] | ||
| - | [[Category: Nucleus]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| - | [[Category: Oxygenase]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription activator/inhibitor]] | [[Category: Transcription activator/inhibitor]] | ||
| - | [[Category: Transcription regulation]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:20:30 2010'' |
Revision as of 11:11, 22 September 2010
FACTOR INHIBITING HIF-1 ALPHA WITH PYRIDINE 2,4 DICARBOXYLIC ACID
Template:ABSTRACT PUBMED 20822901
About this Structure
2W0X is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Conejo-Garcia A, McDonough MA, Loenarz C, McNeill LA, Hewitson KS, Ge W, Lienard BM, Schofield CJ, Clifton IJ. Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6125-8. Epub 2010 Aug 10. PMID:20822901 doi:10.1016/j.bmcl.2010.08.032
- Elkins JM, Hewitson KS, McNeill LA, Seibel JF, Schlemminger I, Pugh CW, Ratcliffe PJ, Schofield CJ. Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha. J Biol Chem. 2003 Jan 17;278(3):1802-6. Epub 2002 Nov 21. PMID:12446723 doi:http://dx.doi.org/10.1074/jbc.C200644200
Page seeded by OCA on Wed Sep 22 14:20:30 2010
