3k5k
From Proteopedia
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===Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a=== | ===Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a=== | ||
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| + | {{ABSTRACT_PUBMED_19891491}} | ||
==About this Structure== | ==About this Structure== | ||
3K5K is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K5K OCA]. | 3K5K is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K5K OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19891491</ref><references group="xtra"/> | ||
[[Category: Histone-lysine N-methyltransferase]] | [[Category: Histone-lysine N-methyltransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Wasney,G A.]] | [[Category: Wasney,G A.]] | ||
[[Category: Weigelt,J.]] | [[Category: Weigelt,J.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Ank repeat]] | [[Category: Ank repeat]] | ||
[[Category: Chromatin regulator]] | [[Category: Chromatin regulator]] | ||
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[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: S-adenosyl-l-methionine]] | [[Category: S-adenosyl-l-methionine]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
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[[Category: Structural genomics consortium]] | [[Category: Structural genomics consortium]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | [[Category: Zinc]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:09:42 2010'' |
Revision as of 07:02, 18 August 2010
Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a
Template:ABSTRACT PUBMED 19891491
About this Structure
3K5K is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liu F, Chen X, Allali-Hassani A, Quinn AM, Wasney GA, Dong A, Barsyte D, Kozieradzki I, Senisterra G, Chau I, Siarheyeva A, Kireev DB, Jadhav A, Herold JM, Frye SV, Arrowsmith CH, Brown PJ, Simeonov A, Vedadi M, Jin J. Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a. J Med Chem. 2009 Dec 24;52(24):7950-3. PMID:19891491 doi:10.1021/jm901543m
Page seeded by OCA on Wed Aug 18 11:09:42 2010
Categories: Histone-lysine N-methyltransferase | Homo sapiens | Allali-Hassani,A. | Arrowsmith,C H. | Bochkarev,A. | Bountra,C. | Brown,P J. | Chau,I. | Chen,X. | Dong,A. | Edwards,A M. | Frye,S V. | Jin,J. | Liu,F. | Senisterra,G. | Vedadi,M. | Wasney,G A. | Weigelt,J. | Ank repeat | Chromatin regulator | G9a | Histone lysine methyltransferase | Metal-binding | Methyltransferase | Nucleus | Phosphoprotein | S-adenosyl-l-methionine | Sgc | Structural genomic | Structural genomics consortium | Transferase
