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3kcg
From Proteopedia
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{{STRUCTURE_3kcg| PDB=3kcg | SCENE= }} | {{STRUCTURE_3kcg| PDB=3kcg | SCENE= }} | ||
===Crystal structure of the antithrombin-factor IXa-pentasaccharide complex=== | ===Crystal structure of the antithrombin-factor IXa-pentasaccharide complex=== | ||
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{{ABSTRACT_PUBMED_20080729}} | {{ABSTRACT_PUBMED_20080729}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hemophilia B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300746 300746]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3kcg]] is a 3 chain structure of [[Antithrombin]] and [[Factor IX]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KCG OCA]. | |
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| + | ==See Also== | ||
| + | *[[Antithrombin|Antithrombin]] | ||
| + | *[[Factor IX|Factor IX]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020080729</ref><references group="xtra"/> |
[[Category: Coagulation factor IXa]] | [[Category: Coagulation factor IXa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Johnson, D J.D.]] | [[Category: Johnson, D J.D.]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
[[Category: Egf-like domain]] | [[Category: Egf-like domain]] | ||
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[[Category: Heparin-binding]] | [[Category: Heparin-binding]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase inhibitor]] | ||
[[Category: Michaelis complex]] | [[Category: Michaelis complex]] | ||
| - | [[Category: Pharmaceutical]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Protease inhibitor]] | [[Category: Protease inhibitor]] | ||
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[[Category: Thrombophilia]] | [[Category: Thrombophilia]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 09:34:14 2010'' | ||
Revision as of 18:05, 25 July 2012
Contents |
Crystal structure of the antithrombin-factor IXa-pentasaccharide complex
Template:ABSTRACT PUBMED 20080729
About this Structure
3kcg is a 3 chain structure of Antithrombin and Factor IX with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Johnson DJ, Langdown J, Huntington JA. Molecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-A structure of the ternary complex. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):645-50. Epub 2009 Dec 22. PMID:20080729
Categories: Coagulation factor IXa | Homo sapiens | Huntington, J A. | Johnson, D J.D. | Blood coagulation | Disulfide bond | Egf-like domain | Glycoprotein | Hemophilia | Heparin-binding | Hydrolase | Hydrolase inhibitor | Michaelis complex | Protease | Protease inhibitor | Secreted | Serine protease | Serine protease inhibitor | Sulfation | Thrombophilia | Zymogen
