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User:Amy Kerzmann/Sandbox 5
From Proteopedia
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<center>'''Elastase''', resolution 1.78 Å (<scene name='User:Amy_Kerzmann/Sandbox_5/Elastase/2'>initial scene</scene>).</center><applet load='4est' size='300' frame='true' align='right' scene='User:Amy_Kerzmann/Sandbox_5/Elastase/2' /></td><td bgcolor='#eeeeee'></td></table> | <center>'''Elastase''', resolution 1.78 Å (<scene name='User:Amy_Kerzmann/Sandbox_5/Elastase/2'>initial scene</scene>).</center><applet load='4est' size='300' frame='true' align='right' scene='User:Amy_Kerzmann/Sandbox_5/Elastase/2' /></td><td bgcolor='#eeeeee'></td></table> | ||
| - | Serine proteases perform their catalytic roles using three key residues: Ser | + | Serine proteases perform their catalytic roles using three key residues: Ser, His, Asp. Because the proteases utilize these three residues for function, they are referred to as the '''catalytic triad'''. Highlight the <scene name='User:Amy_Kerzmann/Sandbox_5/Chymotrypsin-triad/2' target='0'>chymotrypsin catalytic triad</scene>. Mouse over the structure to determine the residue numbers for Ser, Asp and His. |
Now compare chymotrypsin to <scene name='User:Amy_Kerzmann/Sandbox_5/Trypsin-wt-triad/1' target='1'>trypsin catalytic triad</scene>. The <scene name='User:Amy_Kerzmann/Sandbox_5/Elastase-triad/2' target='2'>elastase catalytic triad</scene>. | Now compare chymotrypsin to <scene name='User:Amy_Kerzmann/Sandbox_5/Trypsin-wt-triad/1' target='1'>trypsin catalytic triad</scene>. The <scene name='User:Amy_Kerzmann/Sandbox_5/Elastase-triad/2' target='2'>elastase catalytic triad</scene>. | ||
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{ | { | ||
|type="{}"} | |type="{}"} | ||
| - | What are the residue numbers of the catalytic triad? Provide in the order shown: Ser, | + | What are the residue numbers of the catalytic triad? Provide in the order shown: Ser, His, then Asp. |
| - | { 195, 102 | + | { 195, 57, 102|195, 57 and 102 } |
{Which of the following statements is false? | {Which of the following statements is false? | ||
Revision as of 08:17, 10 February 2010
Serine Proteases
Family includes trypsin, chymotrypsin and elastase.
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Serine proteases perform their catalytic roles using three key residues: Ser, His, Asp. Because the proteases utilize these three residues for function, they are referred to as the catalytic triad. Highlight the . Mouse over the structure to determine the residue numbers for Ser, Asp and His.
Now compare chymotrypsin to . The .
