2x39

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2x39.jpg|left|200px]]
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The entry 2x39 is ON HOLD until Paper Publication
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{{STRUCTURE_2x39| PDB=2x39 | SCENE= }}
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Authors: Davies, T.G., McHardy, T., Caldwell, J.J., Cheung, K., Hunter, L.J., Taylor, K., Rowlands, M., Ruddle, R., Henley, A., Brandon, A.D., Valenti, M., Fazal, L., Seavers, L., Raynaud, F.I., Eccles, S.A., Aherne, G.W., Garrett, M.D., Collins, I.
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===STRUCTURE OF 4-AMINO-N-(4-CHLOROBENZYL)-1-(7H-PYRROLO(2,3-D) PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE BOUND TO PKB===
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Description: Structure of 4-Amino-N-(4-chlorobenzyl)-1-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)piperidine-4-carboxamide bound to PKB
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 16:52:45 2010''
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{{ABSTRACT_PUBMED_20151677}}
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==About this Structure==
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2X39 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X39 OCA].
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==Reference==
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<ref group="xtra">PMID:20151677</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Aherne, G W.]]
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[[Category: Brandon, A D.]]
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[[Category: Caldwell, J J.]]
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[[Category: Cheung, K M.]]
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[[Category: Collins, I.]]
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[[Category: Davies, T G.]]
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[[Category: Eccles, S A.]]
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[[Category: Fazal, L.]]
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[[Category: Garrett, M D.]]
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[[Category: Henley, A.]]
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[[Category: Hunter, L J.]]
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[[Category: Mchardy, T.]]
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[[Category: Raynaud, F I.]]
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[[Category: Rowlands, M.]]
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[[Category: Ruddle, R.]]
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[[Category: Seavers, L.]]
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[[Category: Taylor, K.]]
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[[Category: Valenti, M.]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Wnt signaling pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:41:17 2010''

Revision as of 11:41, 25 February 2010

Image:2x39.jpg

Template:STRUCTURE 2x39

STRUCTURE OF 4-AMINO-N-(4-CHLOROBENZYL)-1-(7H-PYRROLO(2,3-D) PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE BOUND TO PKB

Template:ABSTRACT PUBMED 20151677

About this Structure

2X39 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • McHardy T, Caldwell JJ, Cheung KM, Hunter LJ, Taylor K, Rowlands M, Ruddle R, Henley A, de Haven Brandon A, Valenti M, Davies TG, Fazal L, Seavers L, Raynaud FI, Eccles SA, Aherne GW, Garrett MD, Collins I. Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt). J Med Chem. 2010 Feb 12. PMID:20151677 doi:10.1021/jm901788j

Page seeded by OCA on Thu Feb 25 13:41:17 2010

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