3acw

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3acw.jpg|left|200px]]
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The entry 3acw is ON HOLD until Paper Publication
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{{STRUCTURE_3acw| PDB=3acw | SCENE= }}
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Authors: Liu, C.I., Jeng, W.Y., Wang, A.H.J., Oldfield, E.
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===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-651===
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Description: Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-651
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 16:53:41 2010''
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==About this Structure==
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3ACW is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACW OCA].
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==Reference==
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<ref group="xtra">PMID:18276850</ref><ref group="xtra">PMID:19456099</ref><references group="xtra"/>
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[[Category: Staphylococcus aureus]]
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[[Category: Jeng, W Y.]]
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[[Category: Liu, C I.]]
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[[Category: Oldfield, E.]]
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[[Category: Wang, A H.J.]]
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[[Category: Carotenoid biosynthesis]]
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[[Category: Crtm]]
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[[Category: Head-to-head condensation]]
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[[Category: Inhibitor]]
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[[Category: Staphyloxanthin biosynthesis]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:12:15 2010''

Revision as of 11:00, 24 November 2010

Image:3acw.jpg

Template:STRUCTURE 3acw

Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-651

About this Structure

3ACW is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008 Mar 7;319(5868):1391-4. Epub 2008 Feb 14. PMID:18276850
  • Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. J Med Chem. 2009 Jul 9;52(13):3869-80. PMID:19456099 doi:10.1021/jm9001764

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