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2x2m

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Revision as of 12:13, 3 March 2010

Image:2x2m.png

Template:STRUCTURE 2x2m

CRYSTAL STRUCTURE OF PHOSPHORYLATED RET TYROSINE KINASE DOMAIN WITH INHIBITOR

Template:ABSTRACT PUBMED 20117004

About this Structure

2X2M is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mologni L, Rostagno R, Brussolo S, Knowles PP, Kjaer S, Murray-Rust J, Rosso E, Zambon A, Scapozza L, McDonald NQ, Lucchini V, Gambacorti-Passerini C. Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors. Bioorg Med Chem. 2010 Feb 15;18(4):1482-96. Epub 2010 Jan 11. PMID:20117004 doi:10.1016/j.bmc.2010.01.011

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