This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3e50
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3e50.png|left|200px]] | [[Image:3e50.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3e50", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3e50| PDB=3e50 | SCENE= }} | {{STRUCTURE_3e50| PDB=3e50 | SCENE= }} | ||
===Crystal structure of human insulin degrading enzyme in complex with transforming growth factor-alpha=== | ===Crystal structure of human insulin degrading enzyme in complex with transforming growth factor-alpha=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19896952}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19896952 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19896952}} | {{ABSTRACT_PUBMED_19896952}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3e50]] is a 4 chain structure of [[Insulin-Degrading Enzyme]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E50 OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Insulin-Degrading Enzyme|Insulin-Degrading Enzyme]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019896952</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Insulysin]] | [[Category: Insulysin]] | ||
| Line 30: | Line 21: | ||
[[Category: Tang, W J.]] | [[Category: Tang, W J.]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Egf-like domain]] | [[Category: Egf-like domain]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Growth factor]] | [[Category: Growth factor]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-hormone complex]] |
[[Category: Ide]] | [[Category: Ide]] | ||
[[Category: Lipoprotein]] | [[Category: Lipoprotein]] | ||
| Line 43: | Line 33: | ||
[[Category: Mitogen]] | [[Category: Mitogen]] | ||
[[Category: Palmitate]] | [[Category: Palmitate]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Tgf-alpha]] | [[Category: Tgf-alpha]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| - | [[Category: Zinc]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 18:11:27 2010'' | ||
Revision as of 15:32, 27 July 2012
Contents |
Crystal structure of human insulin degrading enzyme in complex with transforming growth factor-alpha
Template:ABSTRACT PUBMED 19896952
About this Structure
3e50 is a 4 chain structure of Insulin-Degrading Enzyme with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. J Mol Biol. 2010 Jan 15;395(2):430-43. Epub 2009 Nov 5. PMID:19896952 doi:10.1016/j.jmb.2009.10.072
Categories: Homo sapiens | Insulysin | Guo, Q. | Manolopoulou,M. | Tang, W J. | Cell membrane | Egf-like domain | Glycoprotein | Growth factor | Hydrolase | Hydrolase-hormone complex | Ide | Lipoprotein | Membrane | Metal-binding | Metalloprotease | Mitogen | Palmitate | Protease | Secreted | Tgf-alpha | Transmembrane
