3ksy
From Proteopedia
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Revision as of 06:29, 24 March 2010
Contents |
Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS)
Template:ABSTRACT PUBMED 20133692
Disease
Known disease associated with this structure: Fibromatosis, gingival OMIM:[182530], Noonan syndrome 4 OMIM:[182530], Noonan-like/multiple giant cell lesion syndrome OMIM:[182530]
About this Structure
3KSY is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gureasko J, Kuchment O, Makino DL, Sondermann H, Bar-Sagi D, Kuriyan J. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless. Proc Natl Acad Sci U S A. 2010 Feb 4. PMID:20133692
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