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3l51
From Proteopedia
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{{STRUCTURE_3l51| PDB=3l51 | SCENE= }} | {{STRUCTURE_3l51| PDB=3l51 | SCENE= }} | ||
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===Crystal Structure of the Mouse Condensin Hinge Domain=== | ===Crystal Structure of the Mouse Condensin Hinge Domain=== | ||
| + | {{ABSTRACT_PUBMED_20139420}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/SMC2_MOUSE SMC2_MOUSE]] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). [[http://www.uniprot.org/uniprot/SMC4_MOUSE SMC4_MOUSE]] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3l51]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L51 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020139420</ref><references group="xtra"/><references/> |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Griese, J J.]] | [[Category: Griese, J J.]] | ||
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[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Cell division]] | [[Category: Cell division]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Dna condensation]] | [[Category: Dna condensation]] | ||
[[Category: Hinge domain]] | [[Category: Hinge domain]] | ||
[[Category: Mitosis]] | [[Category: Mitosis]] | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 09:41:16 2010'' | ||
Revision as of 20:28, 4 April 2013
Contents |
Crystal Structure of the Mouse Condensin Hinge Domain
Template:ABSTRACT PUBMED 20139420
Function
[SMC2_MOUSE] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). [SMC4_MOUSE] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).
About this Structure
3l51 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Griese JJ, Witte G, Hopfner KP. Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins. Nucleic Acids Res. 2010 Jun;38(10):3454-65. Epub 2010 Feb 5. PMID:20139420 doi:10.1093/nar/gkq038
