This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2x0w

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{Seed}}
 
[[Image:2x0w.png|left|200px]]
[[Image:2x0w.png|left|200px]]
Line 20: Line 19:
==About this Structure==
==About this Structure==
-
2X0W is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0W OCA].
+
[[2x0w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0W OCA].
==Reference==
==Reference==
Line 42: Line 41:
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
[[Category: Tumor suppressor]]
[[Category: Tumor suppressor]]
- 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 10:16:31 2010''
 

Revision as of 20:44, 14 March 2011

Image:2x0w.png

Template:STRUCTURE 2x0w

STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 5,6-DIMETHOXY-2-METHYLBENZOTHIAZOLE

Template:ABSTRACT PUBMED 20142040

About this Structure

2x0w is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Basse N, Kaar JL, Settanni G, Joerger AC, Rutherford TJ, Fersht AR. Toward the rational design of p53-stabilizing drugs: probing the surface of the oncogenic Y220C mutant. Chem Biol. 2010 Jan 29;17(1):46-56. PMID:20142040 doi:10.1016/j.chembiol.2009.12.011
  • Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2x0w"
Personal tools