3g4p

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[[Image:3g4p.jpg|left|200px]]
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===OXA-24 beta-lactamase at pH 7.5===
===OXA-24 beta-lactamase at pH 7.5===
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The line below this paragraph, {{ABSTRACT_PUBMED_20822105}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_20822105}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:17374723</ref><references group="xtra"/>
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<ref group="xtra">PMID:20822105</ref><ref group="xtra">PMID:17374723</ref><references group="xtra"/>
[[Category: Acinetobacter baumannii]]
[[Category: Acinetobacter baumannii]]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
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[[Category: Enzyme mechanism]]
[[Category: Enzyme mechanism]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Plasmid]]
 
[[Category: Resistance]]
[[Category: Resistance]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:55:22 2010''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:12:10 2010''

Revision as of 07:02, 13 October 2010

Image:3g4p.png

Template:STRUCTURE 3g4p

OXA-24 beta-lactamase at pH 7.5

Template:ABSTRACT PUBMED 20822105

About this Structure

3G4P is a 1 chain structure with sequence from Acinetobacter baumannii. Full crystallographic information is available from OCA.

Reference

  • Bou G, Santillana E, Sheri A, Beceiro A, Sampson JM, Kalp M, Bethel CR, Distler AM, Drawz SM, Pagadala SR, van den Akker F, Bonomo RA, Romero A, Buynak JD. Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase. J Am Chem Soc. 2010 Sep 29;132(38):13320-31. PMID:20822105 doi:10.1021/ja104092z
  • Santillana E, Beceiro A, Bou G, Romero A. Crystal structure of the carbapenemase OXA-24 reveals insights into the mechanism of carbapenem hydrolysis. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5354-9. Epub 2007 Mar 20. PMID:17374723

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