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From Proteopedia
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Enolase is an enzyme that catalyzes a reaction of glycolysis. Glycolysis converts glucose into two 3-carbon molecules called pyrubate. The energy released during glycolysis is used to make ATP.<ref>{{text book |author=Voet, Donald; Voet, Judith C.; Pratt, Charlotte W.|title=Fundamentals of Biochemistry: Life at the Molecular Level|edition= 3|pages=486|}}</ref> Enolase is used to convert2-phosphoglycerate (2PG) to phosphoenolpyruvate (PEP) in the 9th reaction of glycolysis.<ref>{{text book |author=Voet, Donald; Voet, Judith C.; Pratt, Charlotte W.|title=Fundamentals of Biochemistry: Life at the Molecular Level|edition= 3|pages=500|}}</ref> | Enolase is an enzyme that catalyzes a reaction of glycolysis. Glycolysis converts glucose into two 3-carbon molecules called pyrubate. The energy released during glycolysis is used to make ATP.<ref>{{text book |author=Voet, Donald; Voet, Judith C.; Pratt, Charlotte W.|title=Fundamentals of Biochemistry: Life at the Molecular Level|edition= 3|pages=486|}}</ref> Enolase is used to convert2-phosphoglycerate (2PG) to phosphoenolpyruvate (PEP) in the 9th reaction of glycolysis.<ref>{{text book |author=Voet, Donald; Voet, Judith C.; Pratt, Charlotte W.|title=Fundamentals of Biochemistry: Life at the Molecular Level|edition= 3|pages=500|}}</ref> | ||
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Fold: TIM beta/alpha-barrel | Fold: TIM beta/alpha-barrel | ||
Superfamily: Enolase C-terminal domain-like | Superfamily: Enolase C-terminal domain-like | ||
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Family: Enolase | Family: Enolase | ||
Species: Baker's yeast (Saccharomyces cerevisiae) | Species: Baker's yeast (Saccharomyces cerevisiae) | ||
Revision as of 04:22, 1 March 2010
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| 1one, resolution 1.80Å () | |||||||||
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| Ligands: | , | ||||||||
| Non-Standard Residues: | |||||||||
| Activity: | Phosphopyruvate hydratase, with EC number 4.2.1.11 | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Enolase is an enzyme that catalyzes a reaction of glycolysis. Glycolysis converts glucose into two 3-carbon molecules called pyrubate. The energy released during glycolysis is used to make ATP.[1] Enolase is used to convert2-phosphoglycerate (2PG) to phosphoenolpyruvate (PEP) in the 9th reaction of glycolysis.[2]
Structure
Structural Clasification of Proteins (SCOP) Class: alpha and beta proteins (a/b) Fold: TIM beta/alpha-barrel Superfamily: Enolase C-terminal domain-like
Family: Enolase Species: Baker's yeast (Saccharomyces cerevisiae)
Mechanism
The of enolase as shown, involves Lys 345, Lys 396, Glu 168, Glu 211, and His 159.

