3lc3
From Proteopedia
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{{STRUCTURE_3lc3| PDB=3lc3 | SCENE= }} | {{STRUCTURE_3lc3| PDB=3lc3 | SCENE= }} | ||
===Benzothiophene Inhibitors of Factor IXa=== | ===Benzothiophene Inhibitors of Factor IXa=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hemophilia B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300746 300746]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3lc3]] is a 4 chain structure of [[Factor IX]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LC3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Factor IX|Factor IX]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020121198</ref><references group="xtra"/> |
[[Category: Coagulation factor IXa]] | [[Category: Coagulation factor IXa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Wang, S.]] | [[Category: Wang, S.]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
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[[Category: Hydroxylation]] | [[Category: Hydroxylation]] | ||
[[Category: Peptidase s1]] | [[Category: Peptidase s1]] | ||
| - | [[Category: Pharmaceutical]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
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[[Category: Sulfation]] | [[Category: Sulfation]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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Revision as of 11:36, 27 July 2012
Contents |
Benzothiophene Inhibitors of Factor IXa
Template:ABSTRACT PUBMED 20121198
About this Structure
3lc3 is a 4 chain structure of Factor IX with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wang S, Beck R, Blench T, Burd A, Buxton S, Malic M, Ayele T, Shaikh S, Chahwala S, Chander C, Holland R, Merette S, Zhao L, Blackney M, Watts A. Studies of Benzothiophene Template as Potent Factor IXa (FIXa) Inhibitors in Thrombosis. J Med Chem. 2010 Feb 25;53(4):1465-72. PMID:20121198 doi:10.1021/jm901475e
Categories: Coagulation factor IXa | Homo sapiens | Beck, R. | Wang, S. | Blood coagulation | Cleavage on pair of basic residue | Disease mutation | Disulfide bond | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hemophilia | Hydrolase | Hydrolase-hydrolase inhibitor complex | Hydroxylation | Peptidase s1 | Phosphoprotein | Protease | Protein-inhibitor complex | Secreted | Serine protease | Sulfation | Zymogen
