2i4q
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2i4q.png|left|200px]] | [[Image:2i4q.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2i4q", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2i4q| PDB=2i4q | SCENE= }} | {{STRUCTURE_2i4q| PDB=2i4q | SCENE= }} | ||
===Human renin/PF02342674 complex=== | ===Human renin/PF02342674 complex=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17574423}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17574423 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17574423}} | {{ABSTRACT_PUBMED_17574423}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]], Hyperproreninemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2i4q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4Q OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Renin|Renin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017574423</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
| Line 38: | Line 26: | ||
[[Category: Protein-ligand complex]] | [[Category: Protein-ligand complex]] | ||
[[Category: Renin inhibitor]] | [[Category: Renin inhibitor]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 14:37:40 2010'' | ||
Revision as of 09:10, 20 October 2012
Contents |
Human renin/PF02342674 complex
Template:ABSTRACT PUBMED 17574423
About this Structure
2i4q is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Powell NA, Ciske FL, Cai C, Holsworth DD, Mennen K, Van Huis CA, Jalaie M, Day J, Mastronardi M, McConnell P, Mochalkin I, Zhang E, Ryan MJ, Bryant J, Collard W, Ferreira S, Gu C, Collins R, Edmunds JJ. Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors. Bioorg Med Chem. 2007 Sep 1;15(17):5912-49. Epub 2007 Jun 2. PMID:17574423 doi:10.1016/j.bmc.2007.05.069
