3kee

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[[Image:3kee.jpg|left|200px]]
 
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{{STRUCTURE_3kee| PDB=3kee | SCENE= }}
{{STRUCTURE_3kee| PDB=3kee | SCENE= }}
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===HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435===
===HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435===
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==About this Structure==
==About this Structure==
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3KEE is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEE OCA].
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[[3kee]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEE OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20166108</ref><references group="xtra"/>
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<ref group="xtra">PMID:020166108</ref><references group="xtra"/><references/>
[[Category: Hepacivirin]]
[[Category: Hepacivirin]]
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
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[[Category: Ns4a]]
[[Category: Ns4a]]
[[Category: Tmc435]]
[[Category: Tmc435]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 14:07:38 2010''
 

Revision as of 02:24, 4 April 2013

Template:STRUCTURE 3kee

HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435

About this Structure

3kee is a 8 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Cummings MD, Lindberg J, Lin TI, de Kock H, Lenz O, Lilja E, Fellander S, Baraznenok V, Nystrom S, Nilsson M, Vrang L, Edlund M, Rosenquist A, Samuelsson B, Raboisson P, Simmen K. Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target. Angew Chem Int Ed Engl. 2010 Feb 22;49(9):1652-5. PMID:20166108 doi:10.1002/anie.200906696

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