2x8e

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(New page: '''Unreleased structure''' The entry 2x8e is ON HOLD until Paper Publication Authors: Read, J.A., Breed, J., Haye, H., McCall, E., Rowsell, S., Vallentine, A., White, A. Description: D...)

Revision as of 19:40, 11 August 2010

Image:2x8e.jpg

Template:STRUCTURE 2x8e

DISCOVERY OF A NOVEL CLASS OF TRIAZOLONES AS CHECKPOINT KINASE INHIBITORS - HIT TO LEAD EXPLORATION

Template:ABSTRACT PUBMED 20673630

About this Structure

2X8E is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Oza V, Ashwell S, Brassil P, Breed J, Deng C, Ezhuthachan J, Haye H, Horn C, Janetka J, Lyne P, Newcombe N, Otterbien L, Pass M, Read J, Roswell S, Su M, Toader D, Yu D, Yu Y, Valentine A, Webborn P, White A, Zabludoff S, Zheng X. Discovery of a novel class of triazolones as Checkpoint Kinase inhibitors--hit to lead exploration. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5133-8. Epub 2010 Jul 29. PMID:20673630 doi:10.1016/j.bmcl.2010.07.015

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