Glutamine synthetase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 2: Line 2:
=Rhiannon Khela=
=Rhiannon Khela=
{{STRUCTURE_2gls| PDB=2gls | SCENE=Sandbox_169/2gls/1 }}
{{STRUCTURE_2gls| PDB=2gls | SCENE=Sandbox_169/2gls/1 }}
 +
=Structure=
=Structure=
According to Yahmeshita et. al., the unrefined structure is made of two layrs containing 6 subunits each, for a total of 12 subunits. <ref>PMID:2572586 </ref>
According to Yahmeshita et. al., the unrefined structure is made of two layrs containing 6 subunits each, for a total of 12 subunits. <ref>PMID:2572586 </ref>
-
text text <ref>PMID:8096645 </ref>
+
 
 +
 
 +
=Function=
 +
Glutamine synthetase is an essential enzyme in the cellular nitrogen metabolism and has been found to play a role in both ammonia assimilation and glutamine byosynthesis.<ref>PMID:8096645 </ref>
[[Image:Glutamine-synthesis.jpg]]
[[Image:Glutamine-synthesis.jpg]]

Revision as of 04:49, 24 March 2010

Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell.

Contents

Rhiannon Khela

PDB ID 2gls

Drag the structure with the mouse to rotate
2gls, resolution 3.50Å ()
Ligands:
Activity: Glutamate--ammonia ligase, with EC number 6.3.1.2
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Structure

According to Yahmeshita et. al., the unrefined structure is made of two layrs containing 6 subunits each, for a total of 12 subunits. [1]


Function

Glutamine synthetase is an essential enzyme in the cellular nitrogen metabolism and has been found to play a role in both ammonia assimilation and glutamine byosynthesis.[2] Image:Glutamine-synthesis.jpg

References

  1. ↑ Yamashita MM, Almassy RJ, Janson CA, Cascio D, Eisenberg D. Refined atomic model of glutamine synthetase at 3.5 A resolution. J Biol Chem. 1989 Oct 25;264(30):17681-90. PMID:2572586
  2. ↑ Kumada Y, Benson DR, Hillemann D, Hosted TJ, Rochefort DA, Thompson CJ, Wohlleben W, Tateno Y. Evolution of the glutamine synthetase gene, one of the oldest existing and functioning genes. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):3009-13. PMID:8096645


Image:2gls120.png
Retrieved from "http://52.214.119.220/wiki/index.php/Glutamine_synthetase"
Personal tools