2wpa
From Proteopedia
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===OPTIMISATION OF 6,6-DIMETHYL PYRROLO 3,4-C PYRAZOLES: IDENTIFICATION OF PHA-793887, A POTENT CDK INHIBITOR SUITABLE FOR INTRAVENOUS DOSING=== | ===OPTIMISATION OF 6,6-DIMETHYL PYRROLO 3,4-C PYRAZOLES: IDENTIFICATION OF PHA-793887, A POTENT CDK INHIBITOR SUITABLE FOR INTRAVENOUS DOSING=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2wpa]] is a 4 chain structure of [[Cell Division Protein Kinase 2]] and [[Cyclin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPA OCA]. | |
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| + | ==See Also== | ||
| + | *[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] | ||
| + | *[[Cyclin|Cyclin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020153204</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Serine/threonine-protein 2 kinase]] | [[Category: Serine/threonine-protein 2 kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 19:33, 25 July 2012
Contents |
OPTIMISATION OF 6,6-DIMETHYL PYRROLO 3,4-C PYRAZOLES: IDENTIFICATION OF PHA-793887, A POTENT CDK INHIBITOR SUITABLE FOR INTRAVENOUS DOSING
Template:ABSTRACT PUBMED 20153204
About this Structure
2wpa is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Brasca MG, Albanese C, Alzani R, Amici R, Avanzi N, Ballinari D, Bischoff J, Borghi D, Casale E, Croci V, Fiorentini F, Isacchi A, Mercurio C, Nesi M, Orsini P, Pastori W, Pesenti E, Pevarello P, Roussel P, Varasi M, Volpi D, Vulpetti A, Ciomei M. Optimization of 6,6-dimethyl pyrrolo[3,4-c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing. Bioorg Med Chem. 2010 Mar 1;18(5):1844-53. Epub 2010 Jan 25. PMID:20153204 doi:10.1016/j.bmc.2010.01.042
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Albanese, C. | Alzani, R. | Amici, R. | Avanzi, N. | Ballinari, D. | Bischoff, J. | Borghi, D. | Brasca, M G. | Casale, E. | Ciomei, M. | Croci, V. | Fiorentini, F. | Isacchi, A. | Mercurio, C. | Nesi, M. | Orsini, P. | Pastori, W. | Pesenti, E. | Pevarello, P. | Roussel, P. | Varasi, M. | Volpi, D. | Vulpetti, A. | Atp-binding | Cell cycle | Cyclin | Mitosis | Phosphoprotein | Serine/threonine-protein 2 kinase | Transferase
