3m2w

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'''Unreleased structure'''
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[[Image:3m2w.jpg|left|200px]]
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The entry 3m2w is ON HOLD
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{{STRUCTURE_3m2w| PDB=3m2w | SCENE= }}
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Authors: Kroemer, M., Revesz, L., Be, C., Izaac, A., Huppertz, C., Schlapbach, A., Scheufler, C.
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===Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor===
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Description: Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:38:06 2010''
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{{ABSTRACT_PUBMED_20591669}}
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==About this Structure==
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3M2W is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2W OCA].
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==Reference==
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<ref group="xtra">PMID:20591669</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Be, C.]]
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[[Category: Huppertz, C.]]
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[[Category: Izaac, A.]]
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[[Category: Kroemer, M.]]
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[[Category: Revesz, L.]]
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[[Category: Scheufler, C.]]
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[[Category: Schlapbach, A.]]
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[[Category: Atp-binding]]
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[[Category: Atp-site kinase inhibitor]]
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[[Category: Kinase]]
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[[Category: Novartis compound nvp-bxs169]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Small molecule inhibitor]]
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[[Category: Spiroazetidine-tetracycle]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:37:21 2010''

Revision as of 08:30, 28 July 2010

Image:3m2w.jpg

Template:STRUCTURE 3m2w

Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor

Template:ABSTRACT PUBMED 20591669

About this Structure

3M2W is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Revesz L, Schlapbach A, Aichholz R, Dawson J, Feifel R, Hawtin S, Littlewood-Evans A, Koch G, Kroemer M, Mobitz H, Scheufler C, Velcicky J, Huppertz C. In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4719-23. Epub 2010 Apr 11. PMID:20591669 doi:10.1016/j.bmcl.2010.04.023

Page seeded by OCA on Wed Jul 28 12:37:21 2010

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