Apurinic-Apyrimidinic Endonuclease
From Proteopedia
(Difference between revisions)
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==STRUCTURE AND FUNCTION== | ==STRUCTURE AND FUNCTION== | ||
APE1 works in the base excision repair pathway | APE1 works in the base excision repair pathway | ||
| - | [[Image:BERpath.png|250 px|right]] | ||
<applet load='1de8' size='300' color='white' frame='true' align='left' caption='APE interacting with DNA'/> | <applet load='1de8' size='300' color='white' frame='true' align='left' caption='APE interacting with DNA'/> | ||
| + | [[Image:BERpath.png|250 px|right]] | ||
| - | [[Image:APEmech.png|500 px|right]] | + | [[Image:APEmech.png|500 px|right]] [[Image:APEactivesite.png|500 px|right]] |
| - | [[Image:APEactivesite.png|500 px|right]] | + | |
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==POPULATION VARIENTS== | ==POPULATION VARIENTS== | ||
APE1 HAS BEEN SHOWN TO CLEAVE C-MYC MRNA | APE1 HAS BEEN SHOWN TO CLEAVE C-MYC MRNA | ||
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Revision as of 04:07, 25 March 2010
Contents |
APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1)
INTRODUCTION
APE1 is an endonuclease [1].
STRUCTURE AND FUNCTION
APE1 works in the base excision repair pathway
|
POPULATION VARIENTS
APE1 HAS BEEN SHOWN TO CLEAVE C-MYC MRNA
REFERENCES
- ↑ Barnes,T
Proteopedia Page Contributors and Editors (what is this?)
Mark Barnes, Michal Harel, Alexander Berchansky, David Canner, Jaime Prilusky, Andrea Gorrell, Eran Hodis, Joel L. Sussman
