From Proteopedia

proteopedia linkproteopedia link

Revision as of 04:48, 25 March 2010 (edit) Mark Barnes (Talk | contribs) (→STRUCTURE AND FUNCTION) ← Previous diff		Revision as of 04:49, 25 March 2010 (edit) (undo) Mark Barnes (Talk | contribs) (→APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1)) Next diff →
Line 1:		Line 1:
	=APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1)=		=APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1)=
		+	Intro
		+	Rxn of ape1
		+	The nuclease and redox domain
		+	Gen structure
		+	Substrate binding
	=INTRODUCTION=		=INTRODUCTION=

---

Revision as of 04:49, 25 March 2010

Contents 1 APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) 2 INTRODUCTION 2.1 STRUCTURE AND FUNCTION 2.2 POPULATION VARIENTS 2.3 REFERENCES

APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1)

Intro Rxn of ape1 The nuclease and redox domain Gen structure Substrate binding

INTRODUCTION

APE1 is an endonuclease ^[1].

STRUCTURE AND FUNCTION

APE1 works in the base excision repair pathway

spinqualitylabelsall models APE interacting with DNA Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

POPULATION VARIENTS

APE1 HAS BEEN SHOWN TO CLEAVE C-MYC MRNA

REFERENCES

1. ↑ Barnes,T