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Sandbox 154
From Proteopedia
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== Structure of F-actin == | == Structure of F-actin == | ||
<scene name='Sandbox_154/Thing_in_the_middle/1'>This thing in the middle</scene> | <scene name='Sandbox_154/Thing_in_the_middle/1'>This thing in the middle</scene> | ||
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<applet load='2zwh' size='200' color='white' frame='true' align='right' caption='Filamentous Actin (F-actin)'/> | <applet load='2zwh' size='200' color='white' frame='true' align='right' caption='Filamentous Actin (F-actin)'/> | ||
=== Monomeric Unit - G-actin === | === Monomeric Unit - G-actin === | ||
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<applet load='1j6z' size='200' color='white' frame='true' align='right' caption='Globular Actin (G-actin): PDB identifier [http://www.rcsb.org/pdb/explore/explore.do?structureId=1J6Z/ 1J6Z]. G-actin constitutes the free monomeric form of actin. '/> | <applet load='1j6z' size='200' color='white' frame='true' align='right' caption='Globular Actin (G-actin): PDB identifier [http://www.rcsb.org/pdb/explore/explore.do?structureId=1J6Z/ 1J6Z]. G-actin constitutes the free monomeric form of actin. '/> | ||
=== Domains === | === Domains === | ||
Revision as of 23:48, 25 March 2010
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| 2zwh, resolution 3.30Å () | |||||||
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| Ligands: | , | ||||||
| Non-Standard Residues: | |||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Contents |
F-Actin
Filamentous actin (F-actin) is also referred to as microfilament [1] and is a highly conserved proteinous component found near ubiquitously in eukaryotic cytoskeletons. F-actin and other actin proteins generally provide a structural role to the cell.
History
The F-actin structure was discovered by Straub in 1942. The structure was speculated based on a low-resolution x-ray crystallograph found in 1990 by Holmes et al. The structure was deposited in the PDB databank in Decemeber 2008 by Oda et al. [2].
Introduction
Assembly
Structure of F-actin
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Monomeric Unit - G-actin
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Domains
Function
Enzymatic Role
Active Site
Ligand
Structural Role
References
- ↑ Microfilament - Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Microfilaments. Date accessed: March 16th, 2010.
- ↑ Oda T, Iwasa M, Aihara T, Maéda Y, and Narita A. 2009. The nature of the globular-to fibrous actin transition. Nature,457(7228):441-445. PMID: 19158791
| Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell. |
