2xab

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(New page: '''Unreleased structure''' The entry 2xab is ON HOLD Authors: Murray, C.W., Carr, M.G., Callaghan, O., Chessari, G., Congreve, m., Cowan, S., Coyle, J.E., Downham, R., Figueroa, E., Fre...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:2xab.jpg|left|200px]]
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The entry 2xab is ON HOLD
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{{STRUCTURE_2xab| PDB=2xab | SCENE= }}
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Authors: Murray, C.W., Carr, M.G., Callaghan, O., Chessari, G., Congreve, m., Cowan, S., Coyle, J.E., Downham, R., Figueroa, E., Frederickson, M., Graham, B., McMenamin, R., O'Brian, M.A., Patel, S., Phillips, T.R., Williams, G., Woodhead, A.J., Woolford, A.J.A.
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===STRUCTURE OF HSP90 WITH AN INHIBITOR BOUND===
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Description: Structure of HSP90 with an inhibitor bound
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:15:59 2010''
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{{ABSTRACT_PUBMED_20662534}}
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==About this Structure==
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2XAB is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XAB OCA].
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==Reference==
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<ref group="xtra">PMID:20662534</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Brian, M A.O.]]
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[[Category: Callaghan, O.]]
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[[Category: Carr, M G.]]
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[[Category: Chessari, G.]]
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[[Category: Congreve, M.]]
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[[Category: Cowan, S.]]
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[[Category: Coyle, J E.]]
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[[Category: Downham, R.]]
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[[Category: Figueroa, E.]]
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[[Category: Frederickson, M.]]
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[[Category: Graham, B.]]
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[[Category: Mcmenamin, R.]]
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[[Category: Murray, C W.]]
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[[Category: Patel, S.]]
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[[Category: Phillips, T R.]]
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[[Category: Williams, G.]]
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[[Category: Woodhead, A J.]]
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[[Category: Woolford, A J.A.]]
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[[Category: Atp-binding]]
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[[Category: Cancer]]
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[[Category: Chaperone]]
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[[Category: Nucleotide-binding]]
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[[Category: Stress response]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 11 23:48:33 2010''

Revision as of 19:41, 11 August 2010

Image:2xab.jpg

Template:STRUCTURE 2xab

STRUCTURE OF HSP90 WITH AN INHIBITOR BOUND

Template:ABSTRACT PUBMED 20662534

About this Structure

2XAB is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Woodhead AJ, Angove H, Carr MG, Chessari G, Congreve M, Coyle JE, Cosme J, Graham B, Day PJ, Downham R, Fazal L, Feltell R, Figueroa E, Frederickson M, Lewis J, McMenamin R, Murray CW, O'Brien MA, Parra L, Patel S, Phillips T, Rees DC, Rich S, Smith DM, Trewartha G, Vinkovic M, Williams B, Woolford AJ. Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-di hydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design. J Med Chem. 2010 Jul 28. PMID:20662534 doi:10.1021/jm100060b

Page seeded by OCA on Wed Aug 11 23:48:33 2010

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