3lxk

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3lxk.jpg|left|200px]]
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The entry 3lxk is ON HOLD until Paper Publication
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{{STRUCTURE_3lxk| PDB=3lxk | SCENE= }}
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Authors: Chrencik, J.E., Patny, A., Leung, I.K., Korniski, B., Emmons, T.L., Benson, T.E.
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===Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6===
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Description: Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:20:35 2010''
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{{ABSTRACT_PUBMED_20478313}}
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==Disease==
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Known disease associated with this structure: SCID, autosomal recessive, T-negative/B-positive type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600173 600173]]
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==About this Structure==
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3LXK is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LXK OCA].
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==Reference==
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<ref group="xtra">PMID:20478313</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Benson, T E.]]
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[[Category: Chrencik, J E.]]
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[[Category: Emmons, T L.]]
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[[Category: Korniski, B.]]
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[[Category: Leung, I K.]]
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[[Category: Patny, A.]]
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[[Category: Alternative splicing]]
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[[Category: Atp-binding]]
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[[Category: Cancer]]
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[[Category: Disease mutation]]
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[[Category: Inflammation]]
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[[Category: Jak3]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Pan inhibitor]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Scid]]
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[[Category: Sh2 domain]]
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[[Category: Transferase]]
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[[Category: Tyk2]]
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[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:36:06 2010''

Revision as of 04:31, 2 June 2010

Image:3lxk.jpg

Template:STRUCTURE 3lxk

Contents

Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

Template:ABSTRACT PUBMED 20478313

Disease

Known disease associated with this structure: SCID, autosomal recessive, T-negative/B-positive type OMIM:[600173]

About this Structure

3LXK is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chrencik JE, Patny A, Leung IK, Korniski B, Emmons TL, Hall T, Weinberg RA, Gormley JA, Williams JM, Day JE, Hirsch JL, Kiefer JR, Leone JW, Fischer HD, Sommers CD, Huang HC, Jacobsen EJ, Tenbrink RE, Tomasselli AG, Benson TE. Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J Mol Biol. 2010 Jul 16;400(3):413-33. Epub 2010 May 15. PMID:20478313 doi:10.1016/j.jmb.2010.05.020

Page seeded by OCA on Wed Jun 2 08:36:06 2010

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