3lxs

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3lxs.jpg|left|200px]]
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The entry 3lxs is ON HOLD until Paper Publication
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{{STRUCTURE_3lxs| PDB=3lxs | SCENE= }}
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Authors: Kerr, I.D., Brinen, L.S.
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===Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (WRR483)===
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Description: Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (WRR483)
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:20:37 2010''
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{{ABSTRACT_PUBMED_20856868}}
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==About this Structure==
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3LXS is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2efm 2efm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LXS OCA].
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==Reference==
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<ref group="xtra">PMID:20856868</ref><references group="xtra"/>
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[[Category: Cruzipain]]
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[[Category: Trypanosoma cruzi]]
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[[Category: Brinen, L S.]]
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[[Category: Kerr, I D.]]
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[[Category: Covalent inhibitor]]
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[[Category: Cysteine protease]]
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[[Category: Hydrolase]]
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[[Category: Vinyl sulfonamide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 20 06:31:57 2010''

Revision as of 03:21, 20 October 2010

Image:3lxs.jpg

Template:STRUCTURE 3lxs

Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (WRR483)

Template:ABSTRACT PUBMED 20856868

About this Structure

3LXS is a 2 chains structure with sequences from Trypanosoma cruzi. This structure supersedes the now removed PDB entry 2efm. Full crystallographic information is available from OCA.

Reference

  • Chen YT, Brinen LS, Kerr ID, Hansell E, Doyle PS, McKerrow JH, Roush WR. In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. PLoS Negl Trop Dis. 2010 Sep 14;4(9). pii: e825. PMID:20856868 doi:10.1371/journal.pntd.0000825

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