1ier
From Proteopedia
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| - | [[Image:1ier.gif|left|200px]]<br /><applet load="1ier" size=" | + | [[Image:1ier.gif|left|200px]]<br /><applet load="1ier" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1ier, resolution 2.26Å" /> | caption="1ier, resolution 2.26Å" /> | ||
'''CUBIC CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN'''<br /> | '''CUBIC CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1IER is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus] with CD as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=1:Metal-Binding Site. Site 1 Is Exposed To The Exterior Of ...'>1</scene>, <scene name='pdbsite=2:Metal Site. Site 2 Is Located Near The Inner Surface Of ...'>2</scene> and <scene name='pdbsite=3:Metal-Binding Site Cd 203 Is Located On A Two-Fold Axis ...'>3</scene>. Full crystallographic information is available from [http:// | + | 1IER is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus] with <scene name='pdbligand=CD:'>CD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=1:Metal-Binding+Site.+Site+1+Is+Exposed+To+The+Exterior+Of+...'>1</scene>, <scene name='pdbsite=2:Metal+Site.+Site+2+Is+Located+Near+The+Inner+Surface+Of+...'>2</scene> and <scene name='pdbsite=3:Metal-Binding+Site+Cd+203+Is+Located+On+A+Two-Fold+Axis+...'>3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IER OCA]. |
==Reference== | ==Reference== | ||
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[[Category: iron storage]] | [[Category: iron storage]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 09:50:29 2008'' |
Revision as of 07:50, 3 February 2008
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CUBIC CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN
Overview
Horse-spleen apoferritin is known to crystallize in three different space, groups, cubic F432, tetragonal P42(1)2 and orthorhombic P2(1)2(1)2. A, structure comparison of the cubic and tetragonal forms is presented here., Both crystal forms were obtained by the vapor-diffusion technique and data, were collected at 2.26 A (cubic crystal) and 2.60 A (tetragonal crystal), resolution. Two main differences were observed between these crystal, structures: (i) whereas intermolecular contacts only involve salt-bridge, type interactions via cadmium ions in the cubic structure, two types of, interactions are observed in the tetragonal crystal (cadmium-ion-mediated, salt bridges and hydrogen-bonding interactions) and (ii) cadmium ions, bound in the threefold axes of ferritin molecules exhibit lower, site-occupation factors in the tetragonal structure than in the cubic one.
About this Structure
1IER is a Single protein structure of sequence from Equus caballus with as ligand. Known structural/functional Sites: , and . Full crystallographic information is available from OCA.
Reference
Comparison of the structures of the cubic and tetragonal forms of horse-spleen apoferritin., Granier T, Gallois B, Dautant A, Langlois d'Estaintot B, Precigoux G, Acta Crystallogr D Biol Crystallogr. 1997 Sep 1;53(Pt 5):580-7. PMID:15299889
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