1jlx
From Proteopedia
(Difference between revisions)
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| - | [[Image:1jlx.gif|left|200px]]<br /><applet load="1jlx" size=" | + | [[Image:1jlx.gif|left|200px]]<br /><applet load="1jlx" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1jlx, resolution 2.2Å" /> | caption="1jlx, resolution 2.2Å" /> | ||
'''AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE'''<br /> | '''AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1JLX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Amaranthus_caudatus Amaranthus caudatus] with FOR and MBN as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=S1:Carbohydrate Binding Site'>S1</scene>. Full crystallographic information is available from [http:// | + | 1JLX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Amaranthus_caudatus Amaranthus caudatus] with <scene name='pdbligand=FOR:'>FOR</scene> and <scene name='pdbligand=MBN:'>MBN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=S1:Carbohydrate+Binding+Site'>S1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLX OCA]. |
==Reference== | ==Reference== | ||
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[[Category: t-disaccharide homodimer]] | [[Category: t-disaccharide homodimer]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 09:50:58 2008'' |
Revision as of 07:50, 3 February 2008
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AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE
Overview
Amaranthus caudatus agglutinin contains a novel arrangement of four, beta-trefoil domains. The sugar-binding site provides specificity for the, carcinoma-associated T-antigen disaccharide even when 'masked' by other, sugars.
About this Structure
1JLX is a Single protein structure of sequence from Amaranthus caudatus with and as ligands. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin., Transue TR, Smith AK, Mo H, Goldstein IJ, Saper MA, Nat Struct Biol. 1997 Oct;4(10):779-83. PMID:9334739
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