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3is9
From Proteopedia
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[[Image:3is9.png|left|200px]] | [[Image:3is9.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3is9]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_bh10 Human immunodeficiency virus type 1 bh10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IS9 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Zinc]] | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 21 09:08:35 2010'' | ||
Revision as of 01:08, 27 December 2010
Contents |
Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).
Template:ABSTRACT PUBMED 19775161
About this Structure
3is9 is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus type 1 bh10. Full crystallographic information is available from OCA.
See Also
Reference
- Cullen MD, Ho WC, Bauman JD, Das K, Arnold E, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M. Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. J Med Chem. 2009 Oct 22;52(20):6467-73. PMID:19775161 doi:10.1021/jm901167t
Categories: Human immunodeficiency virus type 1 bh10 | Arnold, E. | Bauman, J D. | Das, K. | Ho, W C. | Adam | Aid | Aspartyl protease | Cell membrane | Cytoplasm | Dna integration | Dna recombination | Dna-directed dna polymerase | Endonuclease | Hiv | Hydrolase | Lipoprotein | Membrane | Metal-binding | Multifunctional enzyme | Myristate | Nnrti | Nonnucleoside inhibitor | Nuclease | Nucleotidyltransferase | Nucleus | P51/p66 | Phosphoprotein | Protease | Rna-binding | Rna-directed dna polymerase | Transferase | Transferase-hydrolase complex | Viral nucleoprotein | Virion | Zinc | Zinc-finger
