2xb8

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2xb8.jpg|left|200px]]
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The entry 2xb8 is ON HOLD until Paper Publication
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{{STRUCTURE_2xb8| PDB=2xb8 | SCENE= }}
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Authors: Otero, J.M., Tizon, L., Llamas-Saiz, A.L., Fox, G.C., Gonzalez-Bello, C., van Raaij, M.J.
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===STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (2R)-2-(4-METHOXYBENZYL)-3-DEHYDROQUINIC ACID===
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Description: Structure of Mycobacterium tuberculosis type II dehydroquinase in complex with inhibitor compound (2R)-2-(4-methoxybenzyl)-3-dehydroquinic acid
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 21 09:23:44 2010''
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{{ABSTRACT_PUBMED_20815012}}
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==About this Structure==
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2XB8 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XB8 OCA].
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==Reference==
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<ref group="xtra">PMID:20815012</ref><ref group="xtra">PMID:8064862</ref><ref group="xtra">PMID:1329726</ref><references group="xtra"/>
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[[Category: 3-dehydroquinate dehydratase]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Fox, G C.]]
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[[Category: Gonzalez-Bello, C.]]
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[[Category: Llamas-Saiz, A L.]]
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[[Category: Otero, J M.]]
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[[Category: Raaij, M J.Van.]]
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[[Category: Tizon, L.]]
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[[Category: Amino acid biosynthesis]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:46:20 2010''

Revision as of 07:37, 15 September 2010

Image:2xb8.jpg

Template:STRUCTURE 2xb8

STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (2R)-2-(4-METHOXYBENZYL)-3-DEHYDROQUINIC ACID

Template:ABSTRACT PUBMED 20815012

About this Structure

2XB8 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Peon A, Otero JM, Tizon L, Prazeres VF, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, Gago F, Castedo L, Gonzalez-Bello C. Understanding the Key Factors that Control the Inhibition of Type II Dehydroquinase by (2R)-2-Benzyl-3-dehydroquinic Acids. ChemMedChem. 2010 Sep 2. PMID:20815012 doi:10.1002/cmdc.201000281
  • Gourley DG, Coggins JR, Isaacs NW, Moore JD, Charles IG, Hawkins AR. Crystallization of a type II dehydroquinase from Mycobacterium tuberculosis. J Mol Biol. 1994 Aug 19;241(3):488-91. PMID:8064862 doi:http://dx.doi.org/10.1006/jmbi.1994.1524
  • Moore JD, Lamb HK, Garbe T, Servos S, Dougan G, Charles IG, Hawkins AR. Inducible overproduction of the Aspergillus nidulans pentafunctional AROM protein and the type-I and -II 3-dehydroquinases from Salmonella typhi and Mycobacterium tuberculosis. Biochem J. 1992 Oct 1;287 ( Pt 1):173-81. PMID:1329726

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