3ly2

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Revision as of 08:06, 5 May 2010

Image:3ly2.png

Template:STRUCTURE 3ly2

Catalytic Domain of Human Phosphodiesterase 4B in Complex with A Coumarin-Based Inhibitor

Template:ABSTRACT PUBMED 20378348

About this Structure

3LY2 is a 8 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Govek SP, Oshiro G, Anzola JV, Beauregard C, Chen J, Coyle AR, Gamache DA, Hellberg MR, Hsien JN, Lerch JM, Liao JC, Malecha JW, Staszewski LM, Thomas DJ, Yanni JM, Noble SA, Shiau AK. Water-soluble PDE4 inhibitors for the treatment of dry eye. Bioorg Med Chem Lett. 2010 May 1;20(9):2928-32. Epub 2010 Mar 7. PMID:20378348 doi:10.1016/j.bmcl.2010.03.023

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