3ioi

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[[Image:3ioi.png|left|200px]]
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{{STRUCTURE_3ioi| PDB=3ioi | SCENE= }}
{{STRUCTURE_3ioi| PDB=3ioi | SCENE= }}
===Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (1GW)===
===Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (1GW)===
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{{ABSTRACT_PUBMED_20364127}}
{{ABSTRACT_PUBMED_20364127}}
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==Disease==
 
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Known disease associated with this structure: Blood group, ABO system OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=110300 110300]]
 
==About this Structure==
==About this Structure==
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3IOI is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IOI OCA].
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[[3ioi]] is a 1 chain structure of [[Galactosyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IOI OCA].
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==See Also==
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*[[Galactosyltransferase|Galactosyltransferase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20364127</ref><references group="xtra"/>
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<ref group="xtra">PMID:020364127</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Jorgensen, R.]]
[[Category: Jorgensen, R.]]
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[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
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[[Category: Polymorphism]]
 
[[Category: Rossman fold]]
[[Category: Rossman fold]]
[[Category: Secreted]]
[[Category: Secreted]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:46:38 2010''
 

Revision as of 01:37, 27 July 2012

Image:3ioi.png

Template:STRUCTURE 3ioi

Contents

Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (1GW)

Template:ABSTRACT PUBMED 20364127

About this Structure

3ioi is a 1 chain structure of Galactosyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Pesnot T, Jorgensen R, Palcic MM, Wagner GK. Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat Chem Biol. 2010 May;6(5):321-3. Epub 2010 Apr 4. PMID:20364127 doi:10.1038/nchembio.343

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OCA

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