3l95

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{{STRUCTURE_3l95| PDB=3l95 | SCENE= }}
{{STRUCTURE_3l95| PDB=3l95 | SCENE= }}
===Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody===
===Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody===
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{{ABSTRACT_PUBMED_20393564}}
{{ABSTRACT_PUBMED_20393564}}
==About this Structure==
==About this Structure==
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3L95 is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L95 OCA].
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[[3l95]] is a 6 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L95 OCA].
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==See Also==
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*[[Antibody|Antibody]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20393564</ref><references group="xtra"/>
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<ref group="xtra">PMID:020393564</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hymowitz, S G.]]
[[Category: Hymowitz, S G.]]
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[[Category: Ank repeat]]
[[Category: Ank repeat]]
[[Category: Antibody]]
[[Category: Antibody]]
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[[Category: Calcium]]
 
[[Category: Cell cycle]]
[[Category: Cell cycle]]
[[Category: Cell membrane]]
[[Category: Cell membrane]]
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[[Category: Sea domain]]
[[Category: Sea domain]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:50:06 2010''
 

Revision as of 15:26, 27 July 2012

Image:3l95.png

Template:STRUCTURE 3l95

Contents

Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody

Template:ABSTRACT PUBMED 20393564

About this Structure

3l95 is a 6 chain structure of Antibody with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW. Therapeutic antibody targeting of individual Notch receptors. Nature. 2010 Apr 15;464(7291):1052-7. PMID:20393564 doi:10.1038/nature08878

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