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3lue

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Revision as of 06:10, 20 May 2010

Image:3lue.png

Template:STRUCTURE 3lue

Contents

Model of alpha-actinin CH1 bound to F-actin

Template:ABSTRACT PUBMED 20383143

Disease

Known disease associated with this structure: Dystonia, juvenile-onset OMIM:[102630], Alpha-actinin-3 deficiency OMIM:[102574], Sprinting performance OMIM:[102574]

About this Structure

3LUE is a 20 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Galkin VE, Orlova A, Salmazo A, Djinovic-Carugo K, Egelman EH. Opening of tandem calponin homology domains regulates their affinity for F-actin. Nat Struct Mol Biol. 2010 May;17(5):614-6. Epub 2010 Apr 11. PMID:20383143 doi:10.1038/nsmb.1789

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