3h3b

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{{Seed}}
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[[Image:3h3b.png|left|200px]]
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[[Image:3h3b.jpg|left|200px]]
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==Disease==
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Known disease associated with this structure: Adenocarcinoma of lung, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164870 164870]], Gastric cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164870 164870]], Glioblastoma, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164870 164870]], Ovarian cancer, somatic, OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164870 164870]]
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The line below this paragraph, {{ABSTRACT_PUBMED_21680730}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 21680730 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21680730}}
==About this Structure==
==About this Structure==
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3H3B is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3B OCA].
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[[3h3b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3B OCA].
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==Reference==
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<ref group="xtra">PMID:021680730</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
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[[Category: Polymorphism]]
 
[[Category: Protein-protein complex]]
[[Category: Protein-protein complex]]
[[Category: Receptor]]
[[Category: Receptor]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 11:03:22 2010''
 

Revision as of 04:46, 28 September 2011

Image:3h3b.png

Template:STRUCTURE 3h3b

Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain

Template:ABSTRACT PUBMED 21680730

About this Structure

3h3b is a 4 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Zhou H, Zha Z, Liu Y, Zhang H, Zhu J, Hu S, Shen G, Cheng L, Niu L, Greene MI, Teng M, Liu J. Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21. J Biol Chem. 2011 Sep 9;286(36):31676-83. Epub 2011 Jun 16. PMID:21680730 doi:10.1074/jbc.M111.235184

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