3ld6
From Proteopedia
Line 12: | Line 12: | ||
===Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole=== | ===Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole=== | ||
+ | |||
+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_20149798}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 20149798 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_20149798}} | ||
==About this Structure== | ==About this Structure== | ||
3LD6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3i3k 3i3k]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LD6 OCA]. | 3LD6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3i3k 3i3k]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LD6 OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:20149798</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Sterol 14-demethylase]] | [[Category: Sterol 14-demethylase]] | ||
Line 49: | Line 58: | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 08:58:41 2010'' |
Revision as of 05:58, 20 May 2010
Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole
Template:ABSTRACT PUBMED 20149798
About this Structure
3LD6 is a 2 chains structure with sequences from Homo sapiens. This structure supersedes the now removed PDB entry 3i3k. Full crystallographic information is available from OCA.
Reference
- Strushkevich N, Usanov SA, Park HW. Structural basis of human CYP51 inhibition by antifungal azoles. J Mol Biol. 2010 Apr 9;397(4):1067-78. Epub 2010 Feb 10. PMID:20149798 doi:10.1016/j.jmb.2010.01.075
Page seeded by OCA on Thu May 20 08:58:41 2010
Categories: Homo sapiens | Sterol 14-demethylase | Arrowsmith, C H. | Bountra, C. | Edwards, A M | MacKenzie, F. | Park, H. | SGC, Structural Genomics Consortium. | Strushkevich, N. | Tempel, W. | Weigelt, J. | Alternative splicing | Cholesterol biosynthesis | Cytochrome p450 | Endoplasmic reticulum | Heme | Iron | Ketoconazole | Lipid synthesis | Membrane | Metal-binding | Microsome | Monooxygenase | Nadp | Oxidoreductase | Polymorphism | Sgc | Steroid biosynthesis | Sterol 14alpha-demethylase | Sterol biosynthesis | Structural genomic | Structural genomics consortium | Transmembrane