3ld6

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===Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole===
===Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole===
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{{ABSTRACT_PUBMED_20149798}}
==About this Structure==
==About this Structure==
3LD6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3i3k 3i3k]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LD6 OCA].
3LD6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3i3k 3i3k]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LD6 OCA].
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==Reference==
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<ref group="xtra">PMID:20149798</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Sterol 14-demethylase]]
[[Category: Sterol 14-demethylase]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
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Revision as of 05:58, 20 May 2010

Template:STRUCTURE 3ld6

Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole

Template:ABSTRACT PUBMED 20149798

About this Structure

3LD6 is a 2 chains structure with sequences from Homo sapiens. This structure supersedes the now removed PDB entry 3i3k. Full crystallographic information is available from OCA.

Reference

  • Strushkevich N, Usanov SA, Park HW. Structural basis of human CYP51 inhibition by antifungal azoles. J Mol Biol. 2010 Apr 9;397(4):1067-78. Epub 2010 Feb 10. PMID:20149798 doi:10.1016/j.jmb.2010.01.075

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