2xbn

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Revision as of 03:43, 7 July 2010

Image:2xbn.png

Template:STRUCTURE 2xbn

INHIBITION OF THE PLP-DEPENDENT ENZYME SERINE PALMITOYLTRANSFERASE BY CYCLOSERINE: EVIDENCE FOR A NOVEL DECARBOXYLATIVE MECHANISM OF INACTIVATION

Template:ABSTRACT PUBMED 20445930

About this Structure

2XBN is a 1 chain structure with sequence from Sphingomonas paucimobilis. Full crystallographic information is available from OCA.

Reference

  • Lowther J, Yard BA, Johnson KA, Carter LG, Bhat VT, Raman MC, Clarke DJ, Ramakers B, McMahon SA, Naismith JH, Campopiano DJ. Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation. Mol Biosyst. 2010 May 5. PMID:20445930 doi:10.1039/c003743e

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