3lxn
From Proteopedia
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{{ABSTRACT_PUBMED_20478313}} | {{ABSTRACT_PUBMED_20478313}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Protein-tyrosine kinase 2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176941 176941]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Pan inhibitor]] | [[Category: Pan inhibitor]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Sh2 domain]] | [[Category: Sh2 domain]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 11:56:15 2010'' |
Revision as of 07:49, 28 July 2010
Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6
Template:ABSTRACT PUBMED 20478313
About this Structure
3LXN is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chrencik JE, Patny A, Leung IK, Korniski B, Emmons TL, Hall T, Weinberg RA, Gormley JA, Williams JM, Day JE, Hirsch JL, Kiefer JR, Leone JW, Fischer HD, Sommers CD, Huang HC, Jacobsen EJ, Tenbrink RE, Tomasselli AG, Benson TE. Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J Mol Biol. 2010 Jul 16;400(3):413-33. Epub 2010 May 15. PMID:20478313 doi:10.1016/j.jmb.2010.05.020
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