3i25
From Proteopedia
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{{STRUCTURE_3i25| PDB=3i25 | SCENE= }} | {{STRUCTURE_3i25| PDB=3i25 | SCENE= }} | ||
===Potent Beta-Secretase 1 hydroxyethylene Inhibitor=== | ===Potent Beta-Secretase 1 hydroxyethylene Inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3i25]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I25 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020122837</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Lindberg, J D.]] | [[Category: Lindberg, J D.]] | ||
[[Category: Nystrom, S.]] | [[Category: Nystrom, S.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Bace]] | [[Category: Bace]] | ||
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[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:34:50 2010'' | ||
Revision as of 17:18, 25 July 2012
Contents |
Potent Beta-Secretase 1 hydroxyethylene Inhibitor
Template:ABSTRACT PUBMED 20122837
About this Structure
3i25 is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bjorklund C, Adolfsson H, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist S, Samuelsson B. Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1' alkoxy residues and an aminoethylene (AE) central core. Bioorg Med Chem. 2010 Feb 15;18(4):1711-23. Epub 2010 Jan 11. PMID:20122837 doi:10.1016/j.bmc.2009.12.051
Categories: Homo sapiens | Memapsin 2 | Borkakoti, N. | Lindberg, J D. | Nystrom, S. | Aspartyl protease | Bace | Beta-secretase | Disulfide bond | Glycoprotein | Hydrolase | Inhibitor | Membrane | Protease | Transmembrane | Zymogen
