3mcv

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===Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+===
===Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+===
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{{ABSTRACT_PUBMED_21123874}}
==About this Structure==
==About this Structure==
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3MCV is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCV OCA].
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[[3mcv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCV OCA].
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==Reference==
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<ref group="xtra">PMID:21123874</ref><references group="xtra"/>
[[Category: Pteridine reductase]]
[[Category: Pteridine reductase]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Hunter, W N.]]
[[Category: Hunter, W N.]]
[[Category: Tulloch, L B.]]
[[Category: Tulloch, L B.]]
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[[Category: Antifolate]]
 
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[[Category: Oxidoreductase]]
 
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[[Category: Pteridine reductase]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:39:27 2010''
 

Revision as of 05:25, 12 January 2011

Template:STRUCTURE 3mcv

Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+

Template:ABSTRACT PUBMED 21123874

About this Structure

3mcv is a 4 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

Reference

  • Dawson A, Tulloch LB, Barrack KL, Hunter WN. High-resolution structures of Trypanosoma brucei pteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug target. Acta Crystallogr D Biol Crystallogr. 2010 Dec;66(Pt 12):1334-40. Epub 2010, Nov 16. PMID:21123874 doi:10.1107/S0907444910040886

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