2bel
From Proteopedia
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| - | [[Image:2bel.gif|left|200px]]<br /><applet load="2bel" size=" | + | [[Image:2bel.gif|left|200px]]<br /><applet load="2bel" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2bel, resolution 2.11Å" /> | caption="2bel, resolution 2.11Å" /> | ||
'''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE'''<br /> | '''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2BEL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with CL, NAP and CBO as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] Known structural/functional Site: <scene name='pdbsite=AC1:Cl Binding Site For Chain C'>AC1</scene>. Full crystallographic information is available from [http:// | + | 2BEL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=CBO:'>CBO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] Known structural/functional Site: <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+C'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BEL OCA]. |
[[Category: 11-beta-hydroxysteroid dehydrogenase]] | [[Category: 11-beta-hydroxysteroid dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: steroid metabolism]] | [[Category: steroid metabolism]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:23:06 2008'' |
Revision as of 08:23, 3 February 2008
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STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE
Disease
Known diseases associated with this structure: Cortisone reductase deficiency OMIM:[600713]
About this Structure
2BEL is a Single protein structure of sequence from Homo sapiens with , and as ligands. Active as 11-beta-hydroxysteroid dehydrogenase, with EC number 1.1.1.146 Known structural/functional Site: . Full crystallographic information is available from OCA.
Page seeded by OCA on Sun Feb 3 10:23:06 2008
Categories: 11-beta-hydroxysteroid dehydrogenase | Homo sapiens | Single protein | Abrahmsen, L. | Arrowsmith, C. | Bray, J. | Debreczeni, J.E. | Delft, F.Von. | Edwards, A. | Elleby, B. | Kavanagh, K. | Oppermann, U. | Sharma, S. | Sundstrom, M. | Svensson, S. | Wu, X. | CBO | CL | NAP | Drug target | Glucocorticoid activation | Hormone metabolism | Inhibitor | Microsome | Nadp | Oxidoreductase | Short-chain dehydrogenase/reductase | Steroid metabolism
