3grw
From Proteopedia
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[[Image:3grw.png|left|200px]] | [[Image:3grw.png|left|200px]] | ||
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{{STRUCTURE_3grw| PDB=3grw | SCENE= }} | {{STRUCTURE_3grw| PDB=3grw | SCENE= }} | ||
===FGFR3 in complex with a Fab=== | ===FGFR3 in complex with a Fab=== | ||
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{{ABSTRACT_PUBMED_19381019}} | {{ABSTRACT_PUBMED_19381019}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Achondroplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], Bladder cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], CATSHL syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], Cervical cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], Colorectal cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], Crouzon syndrome with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], Hypochondroplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], LADD syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], Muenke syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], Nevus, keratinocytic, nonepidermolytic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]], Thanatophoric dysplasia, types I and II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134934 134934]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3grw]] is a 3 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GRW OCA]. | |
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| + | ==See Also== | ||
| + | *[[Antibody|Antibody]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019381019</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Wiesmann, C.]] | [[Category: Wiesmann, C.]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 10:55:16 2010'' | ||
Revision as of 16:17, 27 July 2012
Contents |
FGFR3 in complex with a Fab
Template:ABSTRACT PUBMED 19381019
About this Structure
3grw is a 3 chain structure of Antibody with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Qing J, Du X, Chen Y, Chan P, Li H, Wu P, Marsters S, Stawicki S, Tien J, Totpal K, Ross S, Stinson S, Dornan D, French D, Wang QR, Stephan JP, Wu Y, Wiesmann C, Ashkenazi A. Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J Clin Invest. 2009 May;119(5):1216-29. doi: 10.1172/JCI38017. Epub 2009, Apr 20. PMID:19381019
