3li0

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[[Image:3li0.jpg|left|200px]]
 
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{{STRUCTURE_3li0| PDB=3li0 | SCENE= }}
{{STRUCTURE_3li0| PDB=3li0 | SCENE= }}
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===Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP===
===Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP===
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{{ABSTRACT_PUBMED_20369850}}
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==Function==
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[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
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{{ABSTRACT_PUBMED_20369850}}
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==About this Structure==
==About this Structure==
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3LI0 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LI0 OCA].
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[[3li0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LI0 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20369850</ref><references group="xtra"/>
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<ref group="xtra">PMID:020369850</ref><references group="xtra"/><references/>
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
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[[Category: Mutant r203a]]
[[Category: Mutant r203a]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:40:11 2010''
 

Revision as of 20:45, 4 April 2013

Template:STRUCTURE 3li0

Contents

Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP

Template:ABSTRACT PUBMED 20369850

Function

[PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]

About this Structure

3li0 is a 2 chain structure with sequence from Methanothermobacter thermautotrophicus. Full crystallographic information is available from OCA.

Reference

  • Wood BM, Amyes TL, Fedorov AA, Fedorov EV, Shabila A, Almo SC, Richard JP, Gerlt JA. Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation. Biochemistry. 2010 May 4;49(17):3514-6. PMID:20369850 doi:10.1021/bi100443a

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OCA

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