3mkm

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3mkm.jpg|left|200px]]
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The entry 3mkm is ON HOLD until Paper Publication
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{{STRUCTURE_3mkm| PDB=3mkm | SCENE= }}
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Authors: Garau, G., Fornili, A., Giabbai, B., Degano, M.
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===Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)===
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Description: Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:41:48 2010''
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{{ABSTRACT_PUBMED_21082835}}
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==About this Structure==
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3MKM is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA].
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==Reference==
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<ref group="xtra">PMID:21082835</ref><ref group="xtra">PMID:15130467</ref><ref group="xtra">PMID:16411753</ref><ref group="xtra">PMID:9572842</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
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[[Category: Ribosylpyrimidine nucleosidase]]
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[[Category: Degano, M.]]
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[[Category: Fornili, A.]]
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[[Category: Garau, G.]]
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[[Category: Giabbai, B.]]
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[[Category: Bacterial nucleosidase]]
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[[Category: Hydrolase]]
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[[Category: Metalloenzyme]]
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[[Category: Nucleotide metabolism]]
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[[Category: Pyrimidine nucleoside hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 1 11:30:57 2010''

Revision as of 08:19, 1 December 2010

Image:3mkm.jpg

Template:STRUCTURE 3mkm

Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)

Template:ABSTRACT PUBMED 21082835

About this Structure

3MKM is a 4 chains structure with sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Fornili A, Giabbai B, Garau G, Degano M. Energy Landscapes Associated with Macromolecular Conformational Changes from Endpoint Structures. J Am Chem Soc. 2010 Nov 17. PMID:21082835 doi:10.1021/ja107640u
  • Giabbai B, Degano M. Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy. Structure. 2004 May;12(5):739-49. PMID:15130467 doi:http://dx.doi.org/10.1016/j.str.2004.03.018
  • Muzzolini L, Versees W, Tornaghi P, Van Holsbeke E, Steyaert J, Degano M. New insights into the mechanism of nucleoside hydrolases from the crystal structure of the Escherichia coli YbeK protein bound to the reaction product. Biochemistry. 2006 Jan 24;45(3):773-82. PMID:16411753 doi:10.1021/bi0511991
  • Degano M, Almo SC, Sacchettini JC, Schramm VL. Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor. Biochemistry. 1998 May 5;37(18):6277-85. PMID:9572842 doi:http://dx.doi.org/10.1021/bi973012e

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