3l3m
From Proteopedia
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{{STRUCTURE_3l3m| PDB=3l3m | SCENE= }} | {{STRUCTURE_3l3m| PDB=3l3m | SCENE= }} | ||
===PARP complexed with A927929=== | ===PARP complexed with A927929=== | ||
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{{ABSTRACT_PUBMED_20337371}} | {{ABSTRACT_PUBMED_20337371}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3l3m]] is a 1 chain structure of [[Poly (ADP-ribose) polymerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L3M OCA]. | |
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| + | ==See Also== | ||
| + | *[[Poly (ADP-ribose) polymerase|Poly (ADP-ribose) polymerase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020337371</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Park, C H.]] | [[Category: Park, C H.]] | ||
| - | [[Category: Acetylation]] | ||
[[Category: Adp-ribosylation]] | [[Category: Adp-ribosylation]] | ||
[[Category: Dna damage]] | [[Category: Dna damage]] | ||
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[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:49:54 2010'' | ||
Revision as of 19:38, 26 July 2012
Contents |
PARP complexed with A927929
Template:ABSTRACT PUBMED 20337371
About this Structure
3l3m is a 1 chain structure of Poly (ADP-ribose) polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Penning TD, Zhu GD, Gong J, Thomas S, Gandhi VB, Liu X, Shi Y, Klinghofer V, Johnson EF, Park CH, Fry EH, Donawho CK, Frost DJ, Buchanan FG, Bukofzer GT, Rodriguez LE, Bontcheva-Diaz V, Bouska JJ, Osterling DJ, Olson AM, Marsh KC, Luo Y, Giranda VL. Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor. J Med Chem. 2010 Apr 22;53(8):3142-53. PMID:20337371 doi:10.1021/jm901775y
