3mtc

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{{STRUCTURE_3mtc| PDB=3mtc | SCENE= }}
{{STRUCTURE_3mtc| PDB=3mtc | SCENE= }}
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===Crystal Structure of INPP5B in complex with phosphatidylinositol 4-phosphate===
===Crystal Structure of INPP5B in complex with phosphatidylinositol 4-phosphate===
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==Function==
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[[http://www.uniprot.org/uniprot/I5P2_HUMAN I5P2_HUMAN]] Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events.<ref>PMID:7721860</ref>
==About this Structure==
==About this Structure==
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3MTC is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTC OCA].
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[[3mtc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTC OCA].
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==Reference==
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<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphoinositide 5-phosphatase]]
[[Category: Phosphoinositide 5-phosphatase]]
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 30 13:49:59 2010''
 

Revision as of 21:08, 17 April 2013

Template:STRUCTURE 3mtc

Contents

Crystal Structure of INPP5B in complex with phosphatidylinositol 4-phosphate

Function

[I5P2_HUMAN] Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events.[1]

About this Structure

3mtc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Jefferson AB, Majerus PW. Properties of type II inositol polyphosphate 5-phosphatase. J Biol Chem. 1995 Apr 21;270(16):9370-7. PMID:7721860

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