3kek
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | {{Seed}} | |
| + | [[Image:3kek.jpg|left|200px]] | ||
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3kek", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_3kek| PDB=3kek | SCENE= }} | ||
| - | + | ===Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound=== | |
| - | Description: Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20005097}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20005097 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_20005097}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3KEK is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEK OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20005097</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Collins, B.]] | ||
| + | [[Category: Schnute, M E.]] | ||
| + | [[Category: Shieh, H S.]] | ||
| + | [[Category: Collagen degradation]] | ||
| + | [[Category: Disease mutation]] | ||
| + | [[Category: Disulfide bond]] | ||
| + | [[Category: Extracellular matrix]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Metalloprotease]] | ||
| + | [[Category: No contact to zn]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: S1' inhibitor]] | ||
| + | [[Category: S1' specificity]] | ||
| + | [[Category: Secreted]] | ||
| + | [[Category: Selective mmp-13 inhibitor]] | ||
| + | [[Category: Zymogen]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:47:10 2010'' | ||
Revision as of 03:36, 10 November 2010
Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound
Template:ABSTRACT PUBMED 20005097
About this Structure
3KEK is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Schnute ME, O'Brien PM, Nahra J, Morris M, Howard Roark W, Hanau CE, Ruminski PG, Scholten JA, Fletcher TR, Hamper BC, Carroll JN, Patt WC, Shieh HS, Collins B, Pavlovsky AG, Palmquist KE, Aston KW, Hitchcock J, Rogers MD, McDonald J, Johnson AR, Munie GE, Wittwer AJ, Man CF, Settle SL, Nemirovskiy O, Vickery LE, Agawal A, Dyer RD, Sunyer T. Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg Med Chem Lett. 2010 Jan 15;20(2):576-80. Epub 2009 Nov 22. PMID:20005097 doi:10.1016/j.bmcl.2009.11.081
Page seeded by OCA on Wed Nov 10 06:47:10 2010
Categories: Homo sapiens | Collins, B. | Schnute, M E. | Shieh, H S. | Collagen degradation | Disease mutation | Disulfide bond | Extracellular matrix | Glycoprotein | Hydrolase | Hydrolase-hydrolase inhibitor complex | Metal-binding | Metalloprotease | No contact to zn | Protease | S1' inhibitor | S1' specificity | Secreted | Selective mmp-13 inhibitor | Zymogen
