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Villin

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'''3D Structure of Villin''' <br />
'''3D Structure of Villin''' <br />
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The image at the top is a human Human Supervillin Headpiece ([[3ffn]])
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The image at the top is a Human Supervillin Headpiece ([[2k6n]])
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Villin (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin. Supervillin (SVIL) contains numerous gelsolin-like domains in its C-terminal and interacts with actin. Advillin (AVIL) is another actin-binding protein in the [[Gelsolin]] superfamily which is expressed in the peripheral sensory neurons.
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Villin (VIL) is an actin-binding protein. The images at the top and at the right correspond to one representative Villin structure, ''i.e.'' human supervillin headpiece ([[2k6n]]). It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin. Supervillin (SVIL) contains numerous gelsolin-like domains in its C-terminal and interacts with actin. Advillin (AVIL) is another actin-binding protein in the [[Gelsolin]] superfamily which is expressed in the peripheral sensory neurons.

Revision as of 05:32, 26 July 2010

Image:2k6n.png

Template:STRUCTURE 2k6n

3D Structure of Villin
The image at the top is a Human Supervillin Headpiece (2k6n)


Contents

Villin

Villin (VIL) is an actin-binding protein. The images at the top and at the right correspond to one representative Villin structure, i.e. human supervillin headpiece (2k6n). It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin. Supervillin (SVIL) contains numerous gelsolin-like domains in its C-terminal and interacts with actin. Advillin (AVIL) is another actin-binding protein in the Gelsolin superfamily which is expressed in the peripheral sensory neurons.


3D Structures of Villin

Supervillin

2k6m, 2k6n – hSVIL headpiece– human – NMR


Villin

3fg7 – hVIL gelsolin domains 4-6
1unc – hVIL headpiece
2rjw, 2rjx, 2rjv, 2rjy, 1yu7, 1yu8 – cVIL headpiece (mutant) – chicken
1yu5, 1qqv - cVIL headpiece
1vii, 2vik, 2vil - cVIL headpiece - NMR
2ppz, 2jm0 - VIL headpiece (mutant) – synthetic – NMR
2f4k, 1wy3, 1wy4, 1yrf, 1yri - VIL fragment (mutant) – synthetic


Advillin

1und – hAVIL headpiece

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