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3m2w
From Proteopedia
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| - | + | [[Image:3m2w.png|left|200px]] | |
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{{STRUCTURE_3m2w| PDB=3m2w | SCENE= }} | {{STRUCTURE_3m2w| PDB=3m2w | SCENE= }} | ||
===Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor=== | ===Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor=== | ||
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{{ABSTRACT_PUBMED_20591669}} | {{ABSTRACT_PUBMED_20591669}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3m2w]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2W OCA]. | |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020591669</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Spiroazetidine-tetracycle]] | [[Category: Spiroazetidine-tetracycle]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:37:21 2010'' | ||
Revision as of 00:20, 27 July 2012
Contents |
Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor
Template:ABSTRACT PUBMED 20591669
About this Structure
3m2w is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Revesz L, Schlapbach A, Aichholz R, Dawson J, Feifel R, Hawtin S, Littlewood-Evans A, Koch G, Kroemer M, Mobitz H, Scheufler C, Velcicky J, Huppertz C. In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4719-23. Epub 2010 Apr 11. PMID:20591669 doi:10.1016/j.bmcl.2010.04.023
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Be, C. | Huppertz, C. | Izaac, A. | Kroemer, M. | Revesz, L. | Scheufler, C. | Schlapbach, A. | Atp-binding | Atp-site kinase inhibitor | Kinase | Novartis compound nvp-bxs169 | Nucleotide-binding | Phosphoprotein | Serine/threonine-protein kinase | Small molecule inhibitor | Spiroazetidine-tetracycle | Transferase
